The Microbial Metabolites Database (MiMeDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human microbiome. It is intended to be used for applications in metabolomics, clinical chemistry, biomarker discovery and general education. The database is designed to contain and link metabolite data, microbe data, host data, health and bioactivity data, and exposure data. Many data fields in the database are hyperlinked to other databases (FooDB, HMDB, KEGG, PubChem, MetaCyc, ChEBI, UniProt, and GenBank). The Microbial Metabolites Database supports extensive text, sequence, spectral, chemical structure and relational query searches.

MiMeDB (The Human Microbial Metabolome Database) is a freely available, web-enabled database containing detailed information about the small molecules produced by the human microbiome. Many microbially produced chemicals play important roles in human health and disease with some (such as butyric acid) offering protection against inflammation and cancer and others (such as indoxyl sulfate) causing damage to the kidneys, heart and brain. While all microbes synthesize primary metabolites required for their own survival, they also produce a variety of exotic compounds arising from their ability to grow on many unusual substrates or host-derived food sources. For instance, many of the metabolites produced by human microbes arise from the transformation of xenobiotics arising from human consumption such as food constituents, food additives, phytochemicals, drugs, cosmetics and other exogenous or man-made chemicals. Microbes also chemically transform many host-produced (human) metabolites as well as previously host-transformed (phase I and phase II) xenobiotics. As a result, the human microbiome is believed to produce or process >55,000 different compounds – many of which affect human health, behavior and disease.

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