MiMeDB: Showing metabocard for 4-Phospho-L-aspartic acid (MMDBc0032922)

Record Information

Version

1.0

Status

Detected and Quantified

Creation Date

2021-11-19 04:27:29 UTC

Update Date

2025-01-15 23:17:27 UTC

Metabolite ID

MMDBc0032922

Metabolite Identification

Common Name

4-Phospho-L-aspartic acid

Description

L-Aspartyl-4-phosphate belongs to the class of organic compounds known as aspartic acid and derivatives. Aspartic acid and derivatives are compounds containing an aspartic acid or a derivative thereof resulting from a reaction of aspartic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. L-Aspartyl-4-phosphate is a very strong basic compound (based on its pKa). L-Aspartyl-4-phosphate is involved in both the lysine biosynthesis I and homoserine biosynthesis pathways. L-Aspartyl-4-phosphate is produced from a reaction between L-aspartate and ATP, with ADP as a byproduct. The reaction is catalyzed by aspartate kinase. L-Aspartyl-4-phosphate reacts with NADPH to produce phosphate, L-aspartate-semialdehyde, and NADP+. Aspartate-semialdehyde dehydrogenase catalyzes this reaction.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Not Available

Molecular Formula

C₄H₈NO₇P

Average Mass

213.0826

Monoisotopic Mass

213.0038381

IUPAC Name

Not Available

Traditional Name

Not Available

CAS Registry Number

22138-53-0

SMILES

Not Available

InChI Identifier

InChI=1S/C4H8NO7P/c5-2(4(7)8)1-3(6)12-13(9,10)11/h2H,1,5H2,(H,7,8)(H2,9,10,11)/t2-/m0/s1

InChI Key

IXZNKTPIYKDIGG-REOHCLBHSA-N

Chemical Taxonomy

Functional Ontology

Not Available

Physical Properties

State

Solid

Predicted Properties

Not Available

Spectra

Not Available

Biological Properties

Cellular Locations

Not Available

Biospecimen Locations

Blood
Urine

Tissue Locations

Not Available

Associated OMIM IDs

114500 (Colorectal cancer)
610247 (Eosinophilic esophagitis)

Human Proteins and Enzymes

Protein ID	Protein Name	Protein Type	Uniprot ID	Species

Human Pathways

Pathways

Name	SMPDB/PathBank

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference

Health Effects and Bioactivity

Health Outcome/Bioactivity	Metabolite Response/Effect	Evidence Type	Host and Biospecimen	Data Source	Reference

Microbial Sources

Superkingdom/Kingdom	Phylum	Total species	Hosts and Body Sites	Microbial Links
Eukaryota/Fungi	Ascomycota	6	Human feces; Human saliva	Unknown
Bacteria	Aquificae	1
Bacteria	Firmicutes	4	Human feces; Human
Bacteria	Chlamydiae	3	Human
Bacteria	Actinobacteria	9	Cattle ; Human
Bacteria	Proteobacteria	33	Human ; Human feces
Archaea/Archaea	Euryarchaeota	3
Bacteria	Deinococcus-thermus	2
Bacteria	Spirochaetes	2
Bacteria	Cyanobacteria	1
Bacteria	nah	1

Exposure Sources

Source Type	Activity	Data Source	Reference

Host Biospecimen and Location

Host and Biospecimen	Status	Age	Sex	Health Condition	Data Source	Reference
Human Urine	Detected but not Quantified	Adult (>18 years old)	Both	Normal	HMDB	22624806
Human Urine	Detected but not Quantified	Adult (>18 years old)	Both	Normal	HMDB	22624806
Human Blood	Detected but not Quantified				HMDB

External Links

Not Available

References

Synthesis Reference

Not Available

General References

Bansal P, Morgat A, Axelsen KB, Muthukrishnan V, Coudert E, Aimo L, Hyka-Nouspikel N, Gasteiger E, Kerhornou A, Neto TB, Pozzato M, Blatter MC, Ignatchenko A, Redaschi N, Bridge A: Rhea, the reaction knowledgebase in 2022. Nucleic Acids Res. 2022 Jan 7;50(D1):D693-D700. doi: 10.1093/nar/gkab1016. [PubMed:34755880 ]

Showing metabocard for 4-Phospho-L-aspartic acid (MMDBc0032922)

MOL for #<Metabolite:0x00007f53a1660188>

3D MOL for #<Metabolite:0x00007f53a1660188>

3D SDF for #<Metabolite:0x00007f53a1660188>

3D-SDF for #<Metabolite:0x00007f53a1660188>

PDB for #<Metabolite:0x00007f53a1660188>

3D PDB for #<Metabolite:0x00007f53a1660188>

SMILES for #<Metabolite:0x00007f53a1660188>

INCHI for #<Metabolite:0x00007f53a1660188>

Structure for #<Metabolite:0x00007f53a1660188>

3D Structure for #<Metabolite:0x00007f53a1660188>