MiMeDB: Akkermansia muciniphila (MMDBm0000014)

Microbe Identification

Microbe name

Akkermansia muciniphila

NCBI Taxonomy ID

239935

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Verrucomicrobia

Class

Verrucomicrobiae

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Species

muciniphila

Microbe Properties

Gram staining properties

Positive

Shape

Cocci

Mobility

Flagellar presence

Number of membranes

Oxygen preference

Anaerobe

Optimal temperature

Temperature range

Mesophilic

Habitat

HostAssociated

Biotic relationship

Free living

Cell arrangement

Pairs - Singles

Sporulation

Pairs - Singles

Metabolism

Saccharolytic, fermentative

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Not Available	GutFeeling KnowledgeBase	31509535
Human		Stool	Not Available	Human Microbiome Project	28953883
Human	Large intestine		Not Available	BacDive	34718743
Human	Bladder	Urine	Not Available	Disbiome	28008148
Human	Large intestine	Feces	Not Available	Disbiome	24130822

Health Effects

Host	Related Health Condition	Microbal response/effect	Data Source	Reference
Human	Autism	Elevated	Disbiome	24130822
Human	Colorectal cancer	Elevated	Disbiome	23940645
Human	Crohn's disease	Reduced	Disbiome	27542127
Human	Crohn's disease	Reduced	Disbiome	31329473
Human	Cystic fibrosis	Reduced	Disbiome	24178246
Human	Cystic fibrosis	Reduced	Disbiome	31959989
Human	Multiple system atrophy	Elevated	Disbiome	31680836
Human	Obesity	Reduced	Disbiome	31952432
Human	Parkinson's disease	Elevated	Disbiome	27591074
Human	Parkinson's disease	Elevated	Disbiome	28449715
Human	Psoriasis	Reduced	Disbiome	29130553
Human	Schizophrenia	Elevated	Disbiome	31255682
Human	Schizophrenia	Elevated	Disbiome	32235826
Human	Ulcerative colitis	Reduced	Disbiome	28740343
Human	Ulcerative colitis	Reduced	Disbiome	31329473
Human	Clostridium Difficile Infection	Elevated	Disbiome	32296918
Human	Hyperlipidemia	Reduced	Disbiome	29566154

Related Metabolites

Metabolic Reactions

Reactions

This table shows at most 10 reactions. For the full list of associated reactions:

See All Associated Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0024411	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024415	(S)-4-Amino-5-oxopentanoate	Hydrogen Ion	Glutamyl-tRNA reductase	Reduction	RHEA	34755880
MMDBr0024418	L-Alanine	diphosphate	Alanine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024474	L-Proline	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024568	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024707	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Biotin synthase	Synthesis	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024774	Glycine	Carbon dioxide	Probable glycine dehydrogenase (decarboxylating) subunit 1	Dehydrogenation	RHEA	34755880
MMDBr0024778	(6S)-10-formyltetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methionyl-tRNA formyltransferase	Transfer of a formyl group	RHEA	34755880

Genome Data

Genome Link

MMDBm0000014

Genome Length

2886298 bp

# Predicted Proteins

2451

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

2022-08-25 19:20:56 UTC

Reference

PMID: 17704766

Source Links

GenBank

NZ_AP021898