| Description | Bacteroides dorei is a Gram-negative, rod-shaped bacterium classified as an obligate anaerobe, a chemoheterotroph that derives energy from organic compounds. It thrives in the human gut, specifically in the colon, where it plays a crucial role in the digestion of complex carbohydrates and contributes to the overall health of the microbiome.Bacteroides dorei prefers mesophilic temperatures, typically flourishing in the 30-37°C range, which aligns with the warm conditions found in the human body. This microbe is part of the Bacteroidetes phylum, which is known for its ability to ferment polysaccharides, producing short-chain fatty acids (SCFAs) like butyrate, which are beneficial for gut health and have anti-inflammatory properties. Being a chemoheterotroph, B. dorei relies on organic molecules as its source of carbon and energy, which it obtains from dietary fibers and other complex carbohydrates that humans cannot digest. The bacterium's Gram-negative cell wall structure, characterized by a thin peptidoglycan layer surrounded by an outer membrane, contributes to its resilience and adaptability within the gut environment. Bacteroides dorei is part of a larger community of gut microbiota, where it interacts with other microbial species, influencing metabolic processes and immune responses. Moreover, its presence has been linked to various health outcomes, including obesity and metabolic syndrome, highlighting the delicate balance of gut microbiota composition. Research into Bacteroides dorei may provide insights into therapeutic approaches for gastrointestinal disorders and the development of probiotics tailored to enhance gut health. Its role in fermentative metabolism not only aids in nutrient absorption but also plays a part in maintaining the gut barrier function, which is essential for overall health. |
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