MiMeDB: Candida albicans (MMDBm0000584)

Microbe Identification

Microbe name

Candida albicans

NCBI Taxonomy ID

5476

Microbe Taxonomy

Superkingdom

Eukaryota

Kingdom

Fungi

Phylum

Ascomycota

Class

Saccharomycetes

Order

Saccharomycetales

Family

Debaryomycetaceae

Genus

Candida

Species

albicans

Strain

Not Available

Microbe Properties

Gram staining properties

Positive

Shape

Yeast-like cell, globose to elongate

Mobility

Not Available

Flagellar presence

Not Available

Number of membranes

Not Available

Oxygen preference

Not Available

Optimal temperature

Not Available

Temperature range

Not Available

Habitat

Not Available

Biotic relationship

Not Available

Cell arrangement

Pseudohyphae and occasionally true hyphae

Sporulation

Not Available

Metabolism

Glucose fermentation; Nitrate assimilation

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Unknown	The Human Microbiome Project (HMP)	29178920
Human	Large intestine	Feces	Not Available	Disbiome	28530644
Human	Oral cavity	Saliva	Not Available	Disbiome	31247001
Human	Gingiva	Supragingival plaque	Not Available	Disbiome	31953340
Human	Large intestine	Feces	Not Available	Disbiome	24275714
Human	Large intestine	Feces	Not Available	Disbiome	24475780
Human	Large intestine	Feces	Not Available	Disbiome	26843508

Health Effects

Host	Related Health Condition	Microbal response/effect	Data Source	Reference
Human	Alcoholism	Elevated	Disbiome	28530644
Human	Parkinson's disease	Elevated	Disbiome	31247001
Human	Crohn's disease	Elevated	Disbiome	24275714
Human	Inflammatory bowel disease	Elevated	Disbiome	26843508

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012852	6-Phosphogluconic acid	D-Ribulose 5-phosphate	6-phosphogluconate dehydrogenase, decarboxylating	Dehydrogenation	RHEA	34755880
MMDBr0012882	D-glucosamine 6-phosphate	N-Acetyl-D-Glucosamine 6-Phosphate	Glucosamine 6-phosphate N-acetyltransferase	Acetylation	RHEA	34755880
MMDBr0012916	D-Glyceraldehyde 3-phosphate	aldehydo-D-ribose 5-phosphate	Transketolase	Transfer of ketol group	RHEA	34755880
MMDBr0012970	D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Imidazoleglycerol-phosphate dehydratase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0013034	Inosinic acid	Xanthylic acid	Inosine-5'-monophosphate dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0013105	L-Allysine	Aminoadipic acid	L-2-aminoadipate reductase large subunit	Reduction	RHEA	34755880
MMDBr0013106	L-Allysine	Aminoadipic acid	L-2-aminoadipate reductase large subunit	Reduction	RHEA	34755880
MMDBr0013202	D-threo-Isocitric acid	glyoxylate	Isocitrate lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013224	N-acetyl-alpha-D-glucosamine 1-phosphate	Uridine diphosphate-N-acetylglucosamine	Bifunctional protein GlmU	N-Acetylation; Phosphorylation; Isomerization	RHEA	34755880
MMDBr0013333	N-Acetylglutamic acid	N-Acetyl-L-glutamyl 5-phosphate	Protein ARG5,6, mitochondrial	Phosphorylation	RHEA	34755880
MMDBr0013345	D-Erythrose 4-phosphate	3-deoxy-D-arabino-heptulosonate-7-phosphate	Phospho-2-dehydro-3-deoxyheptonate aldolase AMT16	Aldol addition (or reverse)	RHEA	34755880
MMDBr0013382	(6S)-5,6,7,8-tetrahydrofolic acid	7,8-dihydrofolate monoglutamate	Bifunctional dihydrofolate reductase-thymidylate synthase	Reduction	RHEA	34755880
MMDBr0013431	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	Isomerization	RHEA	34755880
MMDBr0013444	D-Ribose-5-phosphate	Phosphoribosyl pyrophosphate	Ribose-phosphate pyrophosphokinase 1	Phosphorylation	RHEA	34755880
MMDBr0013495	beta-D-Fructose 6-phosphate	beta-D-Fructose 1,6-bisphosphate	ATP-dependent 6-phosphofructokinase	Phosphorylation	RHEA	34755880
MMDBr0013551	Chitin	Chitin	Chitin synthase 1	Synthesis	RHEA	34755880
MMDBr0013568	(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid	Succinic acid	Isocitrate lyase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013790	Oxalacetic acid	Phosphoenolpyruvic acid	Phosphoenolpyruvate carboxykinase (ATP)	Phosphorylation	RHEA	34755880
MMDBr0013908	Guanosine triphosphate	Guanosine diphosphate	GTPase ArgK	Dephosphorylation; Hydrolysis; Nucleic acid synthesis and/or repair	RHEA	34755880
MMDBr0013952	1-(5-phosphoribosyl)-5'-AMP	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	Histidine biosynthesis bifunctional protein HisIE	Hydrolysis; Synthesis	RHEA	34755880
MMDBr0014021	superoxide	Hydrogen peroxide	Methanobactin mb-OB3b	Dismutation	RHEA	34755880
MMDBr0014117	N-Acetyl-L-glutamate 5-semialdehyde	N-Acetyl-L-glutamyl 5-phosphate	Protein ARG5,6, mitochondrial	Reduction	RHEA	34755880
MMDBr0014229	5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate	(2S)-2-[5-Amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid	Phosphoribosylaminoimidazole-succinocarboxamide synthase	Synthesis	RHEA	34755880
MMDBr0014256	1-(5-phosphoribosyl)-ATP	1-(5-phosphoribosyl)-5'-AMP	Phosphoribosyl-ATP pyrophosphatase	Dephosphorylation; Synthesis	RHEA	34755880
MMDBr0014383	N-acetyl-alpha-D-glucosamine 1-phosphate	N-Acetyl-D-Glucosamine 6-Phosphate	Phosphoacetylglucosamine mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014627	L-Allothreonine	Acetaldehyde	Low-specificity L-threonine aldolase	Aldol addition (or reverse); Methylation	RHEA	34755880
MMDBr0015133	3-Isopropylmalate	Ketoleucine	3-isopropylmalate dehydrogenase AMT6	Dehydrogenation	RHEA	34755880
MMDBr0015137	Farnesyl pyrophosphate	squalene	Squalene synthase clz20	Synthesis	RHEA	34755880
MMDBr0015138	Farnesyl pyrophosphate	squalene	Squalene synthase erg9	Synthesis	RHEA	34755880
MMDBr0015139	Farnesyl pyrophosphate	squalene	Squalene synthase clz20	Synthesis	RHEA	34755880
MMDBr0015140	Farnesyl pyrophosphate	squalene	Squalene synthase erg9	Synthesis	RHEA	34755880
MMDBr0015493	3-dehydro-4alpha-methylzymosterol	4alpha-methylzymosterol	3-keto-steroid reductase ERG27	Reduction	RHEA	34755880
MMDBr0015494	3-dehydro-4alpha-methylzymosterol	4alpha-methylzymosterol	3-keto-steroid reductase ERG27	Reduction	RHEA	34755880
MMDBr0016266	L-Allysine	Aminoadipic acid	L-2-aminoadipate reductase large subunit	Reduction	RHEA	34755880
MMDBr0017852	L-Cysteine	gamma-Glutamylcysteine	Glutamate--cysteine ligase EgtA	Ligation	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017887	L-Threonine	Acetaldehyde	Low-specificity L-threonine aldolase	Methylation	RHEA	34755880
MMDBr0017894	L-Histidinol	L-Histidine	Histidinol dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0024346	NAD	Hydrogen Ion	Enoyl-[acyl-carrier-protein] reductase [NADH]	Reduction; Synthesis	RHEA	34755880
MMDBr0024353	L-Glutamic acid	Hydrogen Ion	Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase	Synthesis	RHEA	34755880
MMDBr0024355	L-Tyrosine	Hydrogen Ion	Tyrosine-protein kinase ptk	Phosphorylation	RHEA	34755880
MMDBr0024361	NAD	Hydrogen Ion	Alcohol dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0024363	NAD	Hydrogen Ion	NAD-dependent alcohol dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0024426	Adenosine triphosphate	Hydrogen Ion	Phosphatidylinositol 3-kinase VPS34	Phosphorylation	RHEA	34755880
MMDBr0024441	Hydrogen Ion	NADP(+)	NADPH dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0024444	L-Cysteine	diphosphate	Protein farnesyltransferase subunit beta	Farnesylation	RHEA	34755880
MMDBr0024449	L-Methionine	diphosphate	Methionine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024454	D-Galactose	Galactose 1-phosphate	Galactokinase	Phosphorylation	RHEA	34755880
MMDBr0024474	L-Proline	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024563	NADP(+)	Hydrogen Ion	3-oxoacyl-[acyl-carrier-protein] reductase MabA	Reduction; Synthesis	RHEA	34755880
MMDBr0024586	L-Serine	Hydrogen Ion	Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein	Phosphorylation; Synthesis	RHEA	34755880
MMDBr0024590	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0024628	L-Phenylalanine	Hydrogen Ion	Phenylalanine--tRNA ligase beta subunit	Ligation	RHEA	34755880
MMDBr0024677	L-Cysteine	diphosphate	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	Farnesylation	RHEA	34755880
MMDBr0024723	Malonyl-CoA	Water	Fatty acid synthase beta subunit pkiC	Synthesis	RHEA	34755880
MMDBr0024892	Trehalose	D-Glucose	Trehalase 1	Hydrolysis	RHEA	34755880
MMDBr0025015	Acetyl-CoA	CoA	Fatty acid synthase beta subunit pkiC	Synthesis	RHEA	34755880
MMDBr0025016	Malonyl-CoA	CoA	Malonyl CoA-acyl carrier protein transacylase	Synthesis	RHEA	34755880
MMDBr0025190	S-Adenosylmethionine	S-Adenosylhomocysteine	Ubiquinone biosynthesis O-methyltransferase	Methylation	RHEA	34755880
MMDBr0025191	S-Adenosylmethionine	S-Adenosylhomocysteine	Ubiquinone biosynthesis O-methyltransferase, mitochondrial	Methylation	RHEA	34755880
MMDBr0025193	Adenosine triphosphate	ADP	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0025237	L-Threonine	Hydrogen Ion	Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein	Phosphorylation; Synthesis	RHEA	34755880
MMDBr0025242	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase Nep1	Methylation	RHEA	34755880
MMDBr0025499	Hydrogen Ion	Water	Delta(7)-sterol 5(6)-desaturase	Desaturation	RHEA	34755880
MMDBr0025500	Hydrogen Ion	Water	Delta(7)-sterol 5(6)-desaturase	Desaturation	RHEA	34755880
MMDBr0025946	Guanosine triphosphate	diphosphate	mRNA-capping enzyme subunit alpha	Nucleic acid synthesis and/or repair	RHEA	34755880
MMDBr0025947	Guanosine triphosphate	diphosphate	mRNA-capping enzyme subunit alpha	Not Available	RHEA	34755880
MMDBr0026038	Cyclic AMP	Adenosine monophosphate	3',5'-cyclic-nucleotide phosphodiesterase	Formation of 2'-nucleotide products from 2',3'-cyclic substrates	RHEA	34755880
MMDBr0026039	Cyclic GMP	Guanosine monophosphate	3',5'-cyclic-nucleotide phosphodiesterase	Formation of 2'-nucleotide products from 2',3'-cyclic substrates	RHEA	34755880
MMDBr0026040	Uridine 3',5'-cyclic monophosphate	Uridine 5'-monophosphate	3',5'-cyclic-nucleotide phosphodiesterase	Formation of 2'-nucleotide products from 2',3'-cyclic substrates	RHEA	34755880
MMDBr0026041	Cytidine 3',5'-cyclic monophosphate	Cytidine monophosphate	3',5'-cyclic-nucleotide phosphodiesterase	Formation of 2'-nucleotide products from 2',3'-cyclic substrates	RHEA	34755880
MMDBr0026046	Uridine 5'-diphosphate	Uridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026047	Uridine 5'-diphosphate	Cytidine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026048	Guanosine 3',5'-bis(diphosphate)	Guanosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026085	Deoxyuridine-5'-diphosphate	Deoxyuridine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026086	2'-Deoxycytidine 5'-diphosphate	Deoxycytidine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026087	2'-Deoxyadenosine 5'-diphosphate	Deoxyadenosine triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880
MMDBr0026088	2'-Deoxyguanosine 5'-diphosphate	2'-Deoxyguanosine 5'-triphosphate	Nucleoside diphosphate kinase	Phosphorylation	RHEA	34755880

Genome Data

Genome Link

MMDBm0000584

Genome Length

3233889 bp

# Predicted Proteins

1370

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

2022-08-31 20:23:37 UTC

Reference

PMID: 17704766

Source Links

GenBank

NC_032089