Description | Neisseria subflava is a Gram-negative, non-motile, and rod-shaped bacterium that thrives in a temperature range characteristic of mesophiles, between 25-37°C (77-98.6°F). As a heterotroph, it derives its energy from the breakdown of organic compounds, specifically glucose and other sugars. The energy production process is anaerobic, relying on fermentation to generate ATP. Neisseria subflava is found in various body sites across all species, including the oral cavity, nasopharynx, and genital tract. In humans, it is a common inhabitant of the upper respiratory tract and is often isolated from clinical samples, including conjunctival swabs, throat swabs, and endotracheal aspirates. As an obligate aerobe, Neisseria subflava requires oxygen for growth and survival. It is sensitive to anaerobic conditions and will not grow in the absence of oxygen. In its natural environment, it likely inhabits areas with sufficient oxygen, such as the oral cavity and upper respiratory tract. In addition to its fundamental characteristics, Neisseria subflava is also known for its capacity to bind to epithelial cells and form biofilms. This ability to adhere to surfaces and form communities with other microorganisms contributes to its persistence in various environments and its potential to cause disease. Furthermore, Neisseria subflava has been found to be resistant to various antibiotics, including penicillin and tetracycline, making treatment of infections caused by this microorganism challenging. Its ability to develop resistance to antimicrobial agents highlights the importance of monitoring antibiotic usage and exploring alternative treatment options. In conclusion, Neisseria subflava is a significant microbe that plays a vital role in the human microbiome. Its unique characteristics, including its ability to bind to epithelial cells and form biofilms, make it an important player in maintaining the delicate balance of the respiratory tract. Its resistance to antibiotics also underscores the need for continued research and development of effective treatment strategies. |
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