MiMeDB: Acidothermus cellulolyticus 11B (MMDBm0001177)

Microbe Identification

Microbe name

Acidothermus cellulolyticus 11B

NCBI Taxonomy ID

351607

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Actinobacteria

Class

Actinobacteria

Order

Actinomycetales

Family

Acidothermaceae

Genus

Acidothermus

Species

cellulolyticus

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Not Available

Mobility

Yes

Flagellar presence

Yes

Number of membranes

Oxygen preference

Aerobe

Optimal temperature

Temperature range

Thermophilic

Habitat

Aquatic

Biotic relationship

Free living

Cell arrangement

Not Available

Sporulation

Sporulating

Metabolism

Cellulose degrader - Biomass degrader

Energy source

Not Available

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012860	(2R)-2-phosphoglyceric acid	Phosphoenolpyruvic acid	Enolase	Enolization	RHEA	34755880
MMDBr0012953	(R)-Pantoate	Pantothenic acid	Pantothenate synthetase	Ligation; Phosphorylation; Synthesis	RHEA	34755880
MMDBr0012954	L-Aspartic acid	Argininosuccinic acid	Argininosuccinate synthase	Synthesis	RHEA	34755880
MMDBr0012970	D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate	3-(Imidazol-4-yl)-2-oxopropyl phosphate	Imidazoleglycerol-phosphate dehydratase	Hydration/dehydration of C-O bond; Synthesis	RHEA	34755880
MMDBr0013038	N-(5-Phospho-D-ribosyl)anthranilate	Phosphoribosyl pyrophosphate	Tryptophan biosynthesis protein TrpCD	Transfer of a ribosyl group	RHEA	34755880
MMDBr0013046	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	3-methyl-2-oxobutanoate hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0013083	Glucose 1-phosphate	ADP-alpha-D-glucose	Glucose-1-phosphate adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0013152	L-Glutamic acid	D-Glutamate	L-alanine/L-glutamate racemase	Racemization; Synthesis	RHEA	34755880
MMDBr0013187	Shikimate	Shikimate 3-phosphate	Pentafunctional AROM polypeptide	Phosphorylation	RHEA	34755880
MMDBr0013194	Porphobilinogen	Hydroxymethylbilane	Porphobilinogen deaminase	Deamination	RHEA	34755880
MMDBr0013295	(S)-4-Amino-5-oxopentanoate	5-Aminolevulinic acid	Glutamate-1-semialdehyde 2,1-aminomutase	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0013333	N-Acetylglutamic acid	N-Acetyl-L-glutamyl 5-phosphate	Protein ARG5,6, mitochondrial	Phosphorylation	RHEA	34755880
MMDBr0013362	L-Arabinose	L-Ribulose	L-arabinose isomerase	Isomerization	RHEA	34755880
MMDBr0013395	Pyridoxine 5'-phosphate	Hydrogen peroxide	Probable pyridoxamine 5'-phosphate oxidase	Oxidation	RHEA	34755880
MMDBr0013422	LL-2,6-Diaminoheptanedioate	Meso-2,6-Diaminoheptanedioate	Diaminopimelate epimerase	Epimerization; Racemization	RHEA	34755880
MMDBr0013431	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	Isomerization	RHEA	34755880
MMDBr0013458	Guanosine triphosphate	Guanosine diphosphate	Adenylosuccinate synthetase	Synthesis	RHEA	34755880
MMDBr0013466	Pyridoxamine 5'-phosphate	Hydrogen peroxide	Probable pyridoxamine 5'-phosphate oxidase	Oxidation	RHEA	34755880
MMDBr0013526	Pantothenic acid	(R)-4'-phosphopantothenic acid	Bifunctional enzyme BirA/CoaX	Phosphorylation	RHEA	34755880
MMDBr0013547	Uridine triphosphate	Cytidine triphosphate	CTP synthase	Synthesis	RHEA	34755880
MMDBr0013589	Inositol	scyllo-Inosose	Inositol 2-dehydrogenase	Dehydrogenation	RHEA	34755880
MMDBr0013611	D-Glyceraldehyde 3-phosphate	beta-D-Fructose 6-phosphate	Transaldolase	Transfer of aldol group	RHEA	34755880
MMDBr0013674	Succinic acid	Succinyl-CoA	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial	Ligation	RHEA	34755880
MMDBr0013848	dCTP	dUMP	dCTP deaminase, dUMP-forming	Deamination	RHEA	34755880
MMDBr0013884	L-Aspartic acid	beta-Alanine	L-aspartate decarboxylase dtxS4	Decarboxylation	RHEA	34755880
MMDBr0013886	Carbamoylphosphate	Citrulline	Ornithine carbamoyltransferase	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013929	Uroporphyrinogen III	Coproporphyrinogen III	Uroporphyrinogen decarboxylase	Decarboxylation	RHEA	34755880
MMDBr0013946	Carbamoylphosphate	N-carbamoyl-L-aspartate	Protein pyrABCN	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013952	1-(5-phosphoribosyl)-5'-AMP	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide	Histidine biosynthesis bifunctional protein HisIE	Hydrolysis; Synthesis	RHEA	34755880
MMDBr0014061	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Chorismate	Chorismate synthase	Synthesis	RHEA	34755880
MMDBr0014083	Shikimate 3-phosphate	5-O-(1-Carboxyvinyl)-3-phosphoshikimate	Pentafunctional AROM polypeptide	Synthesis; Dehydration and isomerisation; Oxidation; Phosphorylation; Transfer of a carboxyvinyl group	RHEA	34755880
MMDBr0014117	N-Acetyl-L-glutamate 5-semialdehyde	N-Acetyl-L-glutamyl 5-phosphate	Protein ARG5,6, mitochondrial	Reduction	RHEA	34755880
MMDBr0014193	2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate	thiamine phosphate	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0014251	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	5,10-Methenyltetrahydrofolate	C-1-tetrahydrofolate synthase, cytoplasmic	Synthesis	RHEA	34755880
MMDBr0014257	nicotinate beta-D-ribonucleotide	Nicotinic acid adenine dinucleotide	Probable nicotinate-nucleotide adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0014323	L-Alanine	UDP-N-acetyl-alpha-D-muramoyl-L-alanine	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014333	alpha-D-Glucosamine 1-phosphate	D-glucosamine 6-phosphate	Phosphoglucosamine mutase	Intramolecular transfer of functional group	RHEA	34755880
MMDBr0014369	5,10-Methenyltetrahydrofolate	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Reversible cyclization	RHEA	34755880
MMDBr0014392	2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-C-Methyl-D-erythritol-2,4-cyclodiphosphate	Bifunctional enzyme IspD/IspF	Synthesis	RHEA	34755880
MMDBr0014407	Argininosuccinic acid	fumarate	Bifunctional protein ArgHA	Non-hydrolytic bond cleavage (or its reversal)	RHEA	34755880
MMDBr0014447	Uridine 5'-monophosphate	Uridine 5'-diphosphate	UMP-CMP kinase	Phosphorylation	RHEA	34755880
MMDBr0014486	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014487	(R)-2,3-Dihydroxy-isovalerate	alpha-Ketoisovaleric acid	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014599	Futalosine	dehypoxanthine futalosine	Futalosine hydrolase	Hydrolysis of bond	RHEA	34755880
MMDBr0014619	L-3,4-Dihydroxybutan-2-one 4-phosphate	6,7-Dimethyl-8-(1-D-ribityl)lumazine	6,7-dimethyl-8-ribityllumazine synthase	Synthesis	RHEA	34755880
MMDBr0014621	1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside	Mycothiol	Mycothiol acetyltransferase	N-Acetylation	RHEA	34755880
MMDBr0017922	X-14847	1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside	L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	Ligation	RHEA	34755880
MMDBr0014622	1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside	X-14847	1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase	Deacetylation	RHEA	34755880
MMDBr0014623	1D-myo-inositol 3-phosphate	1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate	D-inositol 3-phosphate glycosyltransferase	Glycosylation	RHEA	34755880
MMDBr0017926	L-Glutamine	Cytidine triphosphate	CTP synthase	Synthesis	RHEA	34755880
MMDBr0014718	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014719	(R)-2,3-Dihydroxy-3-methylpentanoate	2-Keto-3-methyl-valerate	Dihydroxy-acid dehydratase, mitochondrial	Hydration/dehydration of C-O bond	RHEA	34755880
MMDBr0014776	Farnesyl pyrophosphate	Fe(II)-heme o	Protoheme IX farnesyltransferase, mitochondrial	Farnesylation	RHEA	34755880
MMDBr0014783	di-trans,octa-cis-undecaprenyl diphosphate	di-trans,octa-cis-undecaprenyl phosphate	Undecaprenyl-diphosphatase BcrC	Dephosphorylation	RHEA	34755880
MMDBr0014825	di-trans,octa-cis-undecaprenyl phosphate	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	Phospho-N-acetylmuramoyl-pentapeptide-transferase	Transfer of phospho-N-acetylmuramoyl-pentapeptide	RHEA	34755880
MMDBr0015026	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3	RHEA	34755880
MMDBr0017950	aldehydo-D-ribose 5-phosphate	L-Glutamic acid	Pyridoxal 5'-phosphate synthase subunit PDX1	Synthesis	RHEA	34755880
MMDBr0015136	3-Isopropylmalate	2-Isopropylmalic acid	3-isopropylmalate dehydratase large subunit gloJ	Isomerization	RHEA	34755880
MMDBr0015316	L-Aspartate-semialdehyde	(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate	4-hydroxy-tetrahydrodipicolinate synthase	Synthesis	RHEA	34755880
MMDBr0015718	6-amino-6-deoxyfutalosine	Futalosine	Aminodeoxyfutalosine deaminase	Deamination	RHEA	34755880
MMDBr0015916	1-Hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	2-C-Methyl-D-erythritol-2,4-cyclodiphosphate	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)	Synthesis	RHEA	34755880
MMDBr0016358	2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate	thiamine phosphate	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0016359	2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate	thiamine phosphate	Probable thiamine biosynthetic bifunctional enzyme	Synthesis	RHEA	34755880
MMDBr0017834	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	D-Glyceraldehyde 3-phosphate	Tryptophan synthase	Synthesis	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	L-Glutamine	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0024345	L-Tyrosine	Hydrogen Ion	Tyrosine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024389	L-Leucine	diphosphate	Leucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024411	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024415	(S)-4-Amino-5-oxopentanoate	Hydrogen Ion	Glutamyl-tRNA reductase	Reduction	RHEA	34755880
MMDBr0024418	L-Alanine	diphosphate	Alanine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024474	L-Proline	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024539	Tetra-mu3-sulfido-tetrairon(2+)	5'-Deoxyadenosine	Lipoyl synthase	Synthesis	RHEA	34755880
MMDBr0024568	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024578	Adenosine triphosphate	diphosphate	Cysteine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024597	L-Aspartic acid	diphosphate	Aspartate--tRNA(Asp/Asn) ligase	Ligation	RHEA	34755880
MMDBr0024630	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase A	Methylation	RHEA	34755880
MMDBr0024650	di-mu-Sulfido-diiron(1+)	di-mu-Sulfido-diiron(2+)	Ferredoxin--NADP reductase	Dehydrogenation; Reduction	RHEA	34755880
MMDBr0024707	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Biotin synthase	Synthesis	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024778	(6S)-10-formyltetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methionyl-tRNA formyltransferase	Transfer of a formyl group	RHEA	34755880
MMDBr0024779	N-Formyl-L-methionine	formate	Peptide deformylase 1	Removal of the N-terminal formyl group	RHEA	34755880
MMDBr0024782	di-mu-Sulfido-diiron(2+)	di-mu-Sulfido-diiron(1+)	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	Reduction	RHEA	34755880
MMDBr0024789	di-mu-Sulfido-diiron(2+)	di-mu-Sulfido-diiron(1+)	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	Reduction	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024967	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (guanine(37)-N1)-methyltransferase Trm5b	Methylation	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0024974	S-Adenosylmethionine	5'-Deoxyadenosine	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase	Synthesis	RHEA	34755880
MMDBr0024977	S-Adenosylmethionine	5'-Deoxyadenosine	Ribosomal protein S12 methylthiotransferase RimO	Methylthiolation	RHEA	34755880
MMDBr0025060	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025102	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Ribosomal RNA large subunit methyltransferase N	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025145	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Probable dual-specificity RNA methyltransferase RlmN	Methylation	RHEA	34755880
MMDBr0025258	Uridine 5'-monophosphate	L-Cysteine	tRNA-specific 2-thiouridylase MnmA	2-Thiolation of uridine	RHEA	34755880
MMDBr0025326	Guanosine triphosphate	5'-Deoxyadenosine	Probable GTP 3',8-cyclase	Cycle formation	RHEA	34755880
MMDBr0025650	Hydrogen Ion	Hydrogen Ion	NADH-quinone oxidoreductase subunit C/D	Redox reaction	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank