MiMeDB: Thermotoga lettingae TMO (MMDBm0002711)

Microbe Identification

Microbe name

Thermotoga lettingae TMO

NCBI Taxonomy ID

416591

Microbe Taxonomy

Superkingdom

Bacteria

Kingdom

Eubacteria

Phylum

Thermotogae

Class

Thermotogae

Order

Thermotogales

Family

Thermotogaceae

Genus

Thermotoga

Species

lettingae

Strain

Microbe Properties

Gram staining properties

Positive

Shape

Bacilli

Mobility

Flagellar presence

Yes

Number of membranes

Oxygen preference

Anaerobe

Optimal temperature

Temperature range

Hyperthermophilic

Habitat

Specialized

Biotic relationship

Free living

Cell arrangement

Singles

Sporulation

Singles

Metabolism

Methanol degrading

Energy source

Heterotroph

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Expected but not quantified

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0012953	(R)-Pantoate	Pantothenic acid	Pantothenate synthetase	Ligation; Phosphorylation; Synthesis	RHEA	34755880
MMDBr0012954	L-Aspartic acid	Argininosuccinic acid	Argininosuccinate synthase	Synthesis	RHEA	34755880
MMDBr0012989	D-Alanine	D-Alanyl-D-alanine	D-alanine--D-alanine ligase	Ligation	RHEA	34755880
MMDBr0013001	Acetic acid	Acetyl phosphate	Acetate kinase	Transfer of a formyl group	RHEA	34755880
MMDBr0013027	CMP	CDP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0013046	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	3-methyl-2-oxobutanoate hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0013083	Glucose 1-phosphate	ADP-alpha-D-glucose	Glucose-1-phosphate adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0013098	UDP-N-acetyl-alpha-D-muramate	UDP-N-Acetyl-3-(1-carboxyvinyl)-D-glucosamine	UDP-N-acetylenolpyruvoylglucosamine reductase	Reduction	RHEA	34755880
MMDBr0013184	(S)-2,3,4,5-tetrahydrodipicolinate	N_Acetyl_L_2_amino_6_oxopimelate	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	Acetylation	RHEA	34755880
MMDBr0013224	N-acetyl-alpha-D-glucosamine 1-phosphate	Uridine diphosphate-N-acetylglucosamine	Bifunctional protein GlmU	N-Acetylation; Phosphorylation; Isomerization	RHEA	34755880
MMDBr0013246	2-C-methyl-D-erythritol 4-phosphate	1-Deoxy-D-xylulose 5-phosphate	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Isomerization	RHEA	34755880
MMDBr0013248	alpha-D-Glucosamine 1-phosphate	N-acetyl-alpha-D-glucosamine 1-phosphate	Bifunctional protein GlmU	N-Acetylation	RHEA	34755880
MMDBr0013333	N-Acetylglutamic acid	N-Acetyl-L-glutamyl 5-phosphate	Protein ARG5,6, mitochondrial	Phosphorylation	RHEA	34755880
MMDBr0013357	(2R)-3-phosphoglyceric acid	(2R)-3-phospho-glyceroyl phosphate	Phosphoglycerate kinase	Phosphorylation	RHEA	34755880
MMDBr0013458	Guanosine triphosphate	Guanosine diphosphate	Adenylosuccinate synthetase	Synthesis	RHEA	34755880
MMDBr0013529	D-Glutamate	UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamic acid	UDP-N-acetylmuramoylalanine--D-glutamate ligase	Ligation	RHEA	34755880
MMDBr0013611	D-Glyceraldehyde 3-phosphate	beta-D-Fructose 6-phosphate	Transaldolase	Transfer of aldol group	RHEA	34755880
MMDBr0013659	Guanosine triphosphate	7,8-dihydroneopterin 3'-triphosphate	Bifunctional protein FolKE	Hydrolysis	RHEA	34755880
MMDBr0013755	D-Ribose-5-phosphate	Pseudouridine 5'-phosphate	Pseudouridine-5'-phosphate glycosidase	Transfer of a glycosyl group	RHEA	34755880
MMDBr0013768	4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol	2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	Phosphorylation	RHEA	34755880
MMDBr0013801	Phosphoenolpyruvic acid	UDP-N-Acetyl-3-(1-carboxyvinyl)-D-glucosamine	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Synthesis	RHEA	34755880
MMDBr0013809	Ribose-1-phosphate	D-Ribose-5-phosphate	Phosphopentomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0013843	Thymidine	5-Thymidylic acid	Thymidine kinase	Phosphorylation	RHEA	34755880
MMDBr0013884	L-Aspartic acid	beta-Alanine	L-aspartate decarboxylase dtxS4	Decarboxylation	RHEA	34755880
MMDBr0013886	Carbamoylphosphate	Citrulline	Ornithine carbamoyltransferase	Transfer of a carbamoyl group	RHEA	34755880
MMDBr0013921	(R)-4'-phosphopantetheine	3'-dephospho-CoA	Phosphopantetheine adenylyltransferase	Dephosphorylation	RHEA	34755880
MMDBr0013941	S-Methyl-5-thio-alpha-D-ribose 1-phosphate	5-Methylthioribulose 1-phosphate	5-deoxyribose 1-phosphate isomerase	Isomerization	RHEA	34755880
MMDBr0013966	(6S)-5,6,7,8-tetrahydrofolic acid	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Ligation; Synthesis	RHEA	34755880
MMDBr0014117	N-Acetyl-L-glutamate 5-semialdehyde	N-Acetyl-L-glutamyl 5-phosphate	Protein ARG5,6, mitochondrial	Reduction	RHEA	34755880
MMDBr0014126	Glycerol	Glycerol 3-phosphate	Glycerol kinase	Phosphorylation	RHEA	34755880
MMDBr0014251	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	5,10-Methenyltetrahydrofolate	C-1-tetrahydrofolate synthase, cytoplasmic	Synthesis	RHEA	34755880
MMDBr0014257	nicotinate beta-D-ribonucleotide	Nicotinic acid adenine dinucleotide	Probable nicotinate-nucleotide adenylyltransferase	Reversible transfer of an adenylyl group	RHEA	34755880
MMDBr0014282	2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine	5-Aminoimidazole ribonucleotide	Bifunctional purine biosynthetic protein ADE5,7	Ligation	RHEA	34755880
MMDBr0014323	L-Alanine	UDP-N-acetyl-alpha-D-muramoyl-L-alanine	Bifunctional enzyme MurC/Ddl	Ligation	RHEA	34755880
MMDBr0014330	(2R)-O-phospho-3-sulfolactic acid	(2R)-3-sulfolactic acid	Probable 2-phosphosulfolactate phosphatase	Dephosphorylation	RHEA	34755880
MMDBr0014369	5,10-Methenyltetrahydrofolate	(6S)-10-formyltetrahydrofolic acid	C-1-tetrahydrofolate synthase, cytoplasmic	Reversible cyclization	RHEA	34755880
MMDBr0014447	Uridine 5'-monophosphate	Uridine 5'-diphosphate	UMP-CMP kinase	Phosphorylation	RHEA	34755880
MMDBr0017917	5-Aminoimidazole ribonucleotide	4-Amino-2-methyl-5-phosphomethylpyrimidine	Phosphomethylpyrimidine synthase	Synthesis	RHEA	34755880
MMDBr0014514	dCMP	dCDP	Cytidylate kinase	Phosphorylation	RHEA	34755880
MMDBr0014559	beta-D-Ribopyranose	beta-D-ribofuranose	L-fucose mutarotase	Mutarotation	RHEA	34755880
MMDBr0014642	N-acetyl-D-muramate 6-phosphate	D-Lactic acid	N-acetylmuramic acid 6-phosphate etherase	Bond cleavage	RHEA	34755880
MMDBr0014891	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Flavin-dependent thymidylate synthase	Synthesis	RHEA	34755880
MMDBr0015026	di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1->4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 3	RHEA	34755880
MMDBr0017950	aldehydo-D-ribose 5-phosphate	L-Glutamic acid	Pyridoxal 5'-phosphate synthase subunit PDX1	Synthesis	RHEA	34755880
MMDBr0015916	1-Hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	2-C-Methyl-D-erythritol-2,4-cyclodiphosphate	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)	Synthesis	RHEA	34755880
MMDBr0017834	(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate	D-Glyceraldehyde 3-phosphate	Tryptophan synthase	Synthesis	RHEA	34755880
MMDBr0017871	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Serine hydroxymethyltransferase	Methylation	RHEA	34755880
MMDBr0017874	L-Glutamine	L-Glutamic acid	Thermolabile glutaminase	Synthesis	RHEA	34755880
MMDBr0017879	L-Glutamine	2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine	Phosphoribosylformylglycinamidine synthase	Synthesis	RHEA	34755880
MMDBr0017882	Hydrogen carbonate	Carbamoylphosphate	Carbamoyl-phosphate synthase small chain	Synthesis	RHEA	34755880
MMDBr0017897	L-Methionine	S-Adenosylmethionine	S-adenosylmethionine synthase	Synthesis	RHEA	34755880
MMDBr0024360	L-Valine	diphosphate	Valine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024368	L-Isoleucine	diphosphate	Isoleucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024389	L-Leucine	diphosphate	Leucine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024411	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024418	L-Alanine	diphosphate	Alanine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024474	L-Proline	diphosphate	Proline--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024483	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024546	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0024548	(6S)-5,6,7,8-tetrahydrofolic acid	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	Probable aminomethyltransferase	Methylation	RHEA	34755880
MMDBr0024559	Adenosine triphosphate	Hydrogen Ion	Histidine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024568	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024578	Adenosine triphosphate	diphosphate	Cysteine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024593	ADP-alpha-D-glucose	Hydrogen Ion	Probable glycogen synthase	Synthesis	RHEA	34755880
MMDBr0024632	L-Aspartic acid	diphosphate	Aspartate--tRNA(Asp) ligase	Ligation	RHEA	34755880
MMDBr0024666	L-Lysine	diphosphate	Lysine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024745	L-Glutamic acid	diphosphate	Glutamate--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024774	Glycine	Carbon dioxide	Probable glycine dehydrogenase (decarboxylating) subunit 1	Dehydrogenation	RHEA	34755880
MMDBr0024778	(6S)-10-formyltetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methionyl-tRNA formyltransferase	Transfer of a formyl group	RHEA	34755880
MMDBr0024779	N-Formyl-L-methionine	formate	Peptide deformylase 1	Removal of the N-terminal formyl group	RHEA	34755880
MMDBr0024782	di-mu-Sulfido-diiron(2+)	di-mu-Sulfido-diiron(1+)	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	Reduction	RHEA	34755880
MMDBr0024787	L-Threonine	Hydrogen Ion	Threonine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0024789	di-mu-Sulfido-diiron(2+)	di-mu-Sulfido-diiron(1+)	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	Reduction	RHEA	34755880
MMDBr0024813	Dimethylallylpyrophosphate	diphosphate	tRNA dimethylallyltransferase	Transfer of a dimethylallyl group	RHEA	34755880
MMDBr0024826	2-deoxy-alpha-D-ribose 1-phosphate	Deoxyribose 5-phosphate	Phosphopentomutase	Transfers of a phosphate group; Isomerization; Intramolecular transfer of functional group	RHEA	34755880
MMDBr0024925	Glycerol 3-phosphate	Phosphate	Glycerol-3-phosphate acyltransferase	Acylation	RHEA	34755880
MMDBr0024974	S-Adenosylmethionine	5'-Deoxyadenosine	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase	Synthesis	RHEA	34755880
MMDBr0024977	S-Adenosylmethionine	5'-Deoxyadenosine	Ribosomal protein S12 methylthiotransferase RimO	Methylthiolation	RHEA	34755880
MMDBr0025060	L-Serine	Hydrogen Ion	Type-2 serine--tRNA ligase	Ligation	RHEA	34755880
MMDBr0025085	S-Adenosylmethionine	S-Adenosylhomocysteine	Putative ribosomal RNA large subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025102	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Ribosomal RNA large subunit methyltransferase N	Methylation	RHEA	34755880
MMDBr0025105	S-Adenosylmethionine	S-Adenosylhomocysteine	Ribosomal RNA small subunit methyltransferase H	Methylation	RHEA	34755880
MMDBr0025145	di-mu-Sulfido-diiron(1+)	5'-Deoxyadenosine	Probable dual-specificity RNA methyltransferase RlmN	Methylation	RHEA	34755880
MMDBr0025167	L-Lysine	Hydrogen Ion	tRNA(Ile)-lysidine synthase	Synthesis	RHEA	34755880
MMDBr0025258	Uridine 5'-monophosphate	L-Cysteine	tRNA-specific 2-thiouridylase MnmA	2-Thiolation of uridine	RHEA	34755880
MMDBr0025777	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolic acid	(6S)-5,6,7,8-tetrahydrofolic acid	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	Methylation	RHEA	34755880
MMDBr0026022	Adenosine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026023	Cytidine monophosphate	Adenosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026024	Uridine 5'-monophosphate	Uridine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880
MMDBr0026025	Guanosine monophosphate	Guanosine	5'-nucleotidase SurE	Hydrolysis of nucleotide; Dephosphorylation	RHEA	34755880

Genome Data

Genome Link

Not Available

Genome Length

Not Available

# Predicted Proteins

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

Reference

PMID: 17704766

Source Links

GenBank