MiMeDB: Cryptococcus neoformans (MMDBm0148416)

Microbe Identification

Microbe name

Cryptococcus neoformans

NCBI Taxonomy ID

5207

Microbe Taxonomy

Superkingdom

Eukaryota

Kingdom

Fungi

Phylum

Basidiomycota

Class

Tremellomycetes

Order

Tremellales

Family

Cryptococcaceae

Genus

Cryptococcus

Species

neoformans

Microbe Properties

Gram staining properties

Positive

Shape

Yeast-like cell, globose to elongate

Mobility

Flagellar presence

Number of membranes

Not Available

Oxygen preference

Aerobic

Optimal temperature

Not Available

Temperature range

Not Available

Habitat

Marine; Freshwater; Soil; Plant rhizosphere; All plant surface

Biotic relationship

Not Available

Cell arrangement

Absent or rudimentary pseudohyphae

Sporulation

Sporulating (basidiospores); reproduction also by budding

Metabolism

Non-fermentative

Energy source

Osmotrophic

Host and Biospecimens

Host	Body site	Biospecimen	Details	Data Source	Reference
Human	Gut	Feces	Unknown	The Human Microbiome Project (HMP)	29178920
Human	Large intestine	Feces	Not Available	Disbiome	24275714
Human	Gingiva	Supragingival plaque	Not Available	Disbiome	32158514

Health Effects

Host	Related Health Condition	Biospecimen	Microbal response/effect	Data Source	Reference
Human	Crohn's disease		Elevated	Disbiome	24275714

Related Metabolites

Metabolic Reactions

Reactions

Reaction ID	Precursor	Product	Enzyme	Reaction Type	Data Source	Reference
MMDBr0024505	Tetradecanoyl-CoA	Hydrogen Ion	Glycylpeptide N-tetradecanoyltransferase	Transfer of glycylpeptide N-tetradecanoyl group	RHEA	34755880
MMDBr0024351	Chitin	Acetic acid	Chitin deacetylase	Deacetylation	RHEA	34755880
MMDBr0024352	Chitin	Acetic acid	Chitin deacetylase	Deacetylation	RHEA	34755880
MMDBr0024405	Uridine diphosphate glucose	Uridine 5'-diphosphate	Ceramide glucosyltransferase	Transfer of a glucosyl group	RHEA	34755880
MMDBr0024586	L-Serine	Hydrogen Ion	Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein	Phosphorylation; Synthesis	RHEA	34755880
MMDBr0024687	Uridine diphosphate glucose	Uridine 5'-diphosphate	1,3-beta-glucan synthase component FKS1	Synthesis	RHEA	34755880
MMDBr0024843	Hydrogen Ion	Hydrogen Ion	Putative NADH-ubiquinone oxidoreductase MJ0520	Dehydrogenation; Redox reaction	RHEA	34755880
MMDBr0024964	L-Cysteine	CoA	Palmitoyltransferase pfa3	Transfer of a palmitoyl group	RHEA	34755880
MMDBr0025237	L-Threonine	Hydrogen Ion	Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein	Phosphorylation; Synthesis	RHEA	34755880
MMDBr0025723	S-Adenosylmethionine	S-Adenosylhomocysteine	Histone-lysine N-methyltransferase, H3 lysine-9 specific	Methylation	RHEA	34755880
MMDBr0025724	S-Adenosylmethionine	S-Adenosylhomocysteine	Histone-lysine N-methyltransferase, H3 lysine-9 specific	Methylation	RHEA	34755880
MMDBr0025993	S-Adenosylmethionine	S-Adenosylhomocysteine	DNA (cytosine-5-)-methyltransferase DMT5	Methylation	RHEA	34755880
MMDBr0025994	S-Adenosylmethionine	S-Adenosylhomocysteine	DNA (cytosine-5-)-methyltransferase DMT5	Methylation	RHEA	34755880
MMDBr0024343	Adenosine triphosphate	Hydrogen Ion	Serine/threonine-protein kinase ssn3	Phosphorylation	RHEA	34755880
MMDBr0024539	Tetra-mu3-sulfido-tetrairon(2+)	5'-Deoxyadenosine	Lipoyl synthase	Synthesis	RHEA	34755880
MMDBr0024701	Acetyl-CoA	Hydrogen Ion	Histone acetyltransferase rtt109	N-Acetylation	RHEA	34755880
MMDBr0024702	Acetyl-CoA	Hydrogen Ion	Histone acetyltransferase rtt109	N-Acetylation	RHEA	34755880
MMDBr0024720	Uridine diphosphate glucose	Uridine 5'-diphosphate	Sterol 3-beta-glucosyltransferase	Transfer of a glucosyl group	RHEA	34755880
MMDBr0024739	Uridine diphosphate-N-acetylglucosamine	N,N'-diacetylchitobiosyldiphosphodolichol	UDP-N-acetylglucosamine transferase subunit alg13	Transfer of UDP-N-acetylglucosamine	RHEA	34755880
MMDBr0024771	2-hydroxyisobutanoyl-CoA	Hydrogen Ion	tRNA(Met) cytidine acetyltransferase TmcA	N-Acetylation	RHEA	34755880
MMDBr0024772	2-hydroxyisobutanoyl-CoA	Hydrogen Ion	tRNA(Met) cytidine acetyltransferase TmcA	N-Acetylation	RHEA	34755880
MMDBr0024965	L-Histidine	5'-Methylthioadenosine	2-(3-amino-3-carboxypropyl)histidine synthase	Synthesis	RHEA	34755880
MMDBr0024971	L-Threonylcarbamoyladenylate	Hydrogen Ion	tRNA N6-adenosine threonylcarbamoyltransferase	Synthesis	RHEA	34755880
MMDBr0025033	alpha-Ketoglutarate	Formaldehyde	Putative JmjC domain-containing histone demethylation protein 1	Demethylation	RHEA	34755880
MMDBr0025071	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (guanine-N(7)-)-methyltransferase	Methylation	RHEA	34755880
MMDBr0025127	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (adenine(58)-N(1))-methyltransferase TrmI	Methylation	RHEA	34755880
MMDBr0025128	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (guanine(9)-/adenine(9)-N1)-methyltransferase	Methylation	RHEA	34755880
MMDBr0025209	Acetyl-CoA	Hydrogen Ion	N-acetyltransferase Eis	Acetylation	RHEA	34755880
MMDBr0025210	Acetyl-CoA	Hydrogen Ion	Histone acetyltransferase rtt109	N-Acetylation	RHEA	34755880
MMDBr0025299	S-Adenosylmethionine	S-Adenosylhomocysteine	Leucine carboxyl methyltransferase 1	Methylation	RHEA	34755880
MMDBr0025303	S-Adenosylmethionine	S-Adenosylhomocysteine	AdoMet-dependent rRNA methyltransferase spb1	Methylation	RHEA	34755880
MMDBr0025305	NADP(+)	Hydrogen Ion	Very-long-chain 3-oxoacyl-CoA reductase	Reduction	RHEA	34755880
MMDBr0025452	NADP(+)	Uridine 5'-monophosphate	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]	Synthesis	RHEA	34755880
MMDBr0025453	Uridine 5'-monophosphate	NADP(+)	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]	Synthesis	RHEA	34755880
MMDBr0025454	NAD	Uridine 5'-monophosphate	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]	Synthesis	RHEA	34755880
MMDBr0025455	Uridine 5'-monophosphate	NAD	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]	Synthesis	RHEA	34755880
MMDBr0025470	Crotonoyl-CoA	Hydrogen Ion	Histone acetyltransferase esa1	N-Acetylation	RHEA	34755880
MMDBr0025471	Crotonoyl-CoA	Hydrogen Ion	Histone acetyltransferase esa1	N-Acetylation	RHEA	34755880
MMDBr0025719	S-Adenosylmethionine	S-Adenosylhomocysteine	Histone-lysine N-methyltransferase, H3 lysine-4 specific	Methylation	RHEA	34755880
MMDBr0025726	S-Adenosylmethionine	S-Adenosylhomocysteine	Histone-lysine N-methyltransferase, H3 lysine-36 specific	Methylation	RHEA	34755880
MMDBr0025727	S-Adenosylmethionine	S-Adenosylhomocysteine	Histone-lysine N-methyltransferase, H3 lysine-79 specific	Methylation	RHEA	34755880
MMDBr0025945	S-Adenosylmethionine	S-Adenosylhomocysteine	mRNA cap guanine-N7 methyltransferase	Methylation	RHEA	34755880
MMDBr0025973	di-mu-Sulfido-diiron(2+)	di-mu-Sulfido-diiron(1+)	NADPH-dependent diflavin oxidoreductase 1	Redox reaction	RHEA	34755880
MMDBr0025974	di-mu-Sulfido-diiron(2+)	di-mu-Sulfido-diiron(1+)	NADPH-dependent diflavin oxidoreductase 1	Redox reaction	RHEA	34755880
MMDBr0024568	L-Glutamine	L-Glutamic acid	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C	Amide group addition	RHEA	34755880
MMDBr0024967	S-Adenosylmethionine	S-Adenosylhomocysteine	tRNA (guanine(37)-N1)-methyltransferase Trm5b	Methylation	RHEA	34755880
MMDBr0026065	Cytidine triphosphate	Cytidine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026066	Uridine triphosphate	Uridine 5'-monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026067	Adenosine triphosphate	Adenosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026068	Guanosine triphosphate	Guanosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026069	Cytidine triphosphate	Cytidine monophosphate	Inosine triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism	RHEA	34755880
MMDBr0026070	Uridine triphosphate	Uridine 5'-monophosphate	Inosine triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism	RHEA	34755880
MMDBr0026071	Adenosine triphosphate	Adenosine monophosphate	Inosine triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism	RHEA	34755880
MMDBr0026072	Guanosine triphosphate	Guanosine monophosphate	Inosine triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism	RHEA	34755880
MMDBr0026089	Deoxyuridine triphosphate	2'-Deoxyuridine 5'-phosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026090	Deoxycytidine 5'-triphosphate	2'-Deoxycytidine 5'-phosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026091	Deoxyadenosine triphosphate	Deoxyadenosine monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026092	2'-Deoxyguanosine 5'-triphosphate	2'-Deoxyguanosine 5'-monophosphate	Nucleoside triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism; Hydrolysis of pyrophosphate; Dephosphorylation	RHEA	34755880
MMDBr0026093	Deoxyuridine triphosphate	2'-Deoxyuridine 5'-phosphate	Inosine triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism	RHEA	34755880
MMDBr0026094	Deoxycytidine 5'-triphosphate	2'-Deoxycytidine 5'-phosphate	Inosine triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism	RHEA	34755880
MMDBr0026095	Deoxyadenosine triphosphate	Deoxyadenosine monophosphate	Inosine triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism	RHEA	34755880
MMDBr0026096	2'-Deoxyguanosine 5'-triphosphate	2'-Deoxyguanosine 5'-monophosphate	Inosine triphosphate pyrophosphatase	Purine metabolism and pyrimidine metabolism	RHEA	34755880

Genome Data

Genome Link

MMDBm0148416

Genome Length

19418001 bp

# Predicted Proteins

6339

GenBank Sequence Modification Date

17-FEB-2022

MiMeDB Deposition Date

2022-12-08 22:45:43 UTC

Reference

PMID: 17704766

Source Links

GenBank

JAACIV000000000

MiMeDB ID	Organism	Strain	Serotype	Variant	NCBI Taxonomy	BaSyS2 Genome
MMDBm0148585	Cryptococcus neoformans var. grubii	-	-	grubii	178876	View
MMDBm0148780	Cryptococcus neoformans var. grubii H99	H99	-	grubii	235443	View
MMDBm0148853	Cryptococcus neoformans var. neoformans B-3501A	B-3501A	-	neoformans	283643	View
MMDBm0148857	Cryptococcus neoformans var. neoformans JEC21	JEC21	-	neoformans	214684	View