| Description | Bacteroides sp. 1_1_14 is a gram-negative, rod-shaped bacterium that thrives in anaerobic environments, preferring moderate to mesophilic temperature ranges (20-45°C). This microbe is classified as a chemoheterotroph, deriving its energy and carbon from organic compounds, primarily found in the human gastrointestinal tract. As an obligate anaerobe, Bacteroides sp. 1_1_14 can only grow in environments devoid of oxygen, making it well-suited to the complex ecosystems within the human body where oxygen concentrations are minimal. Bacteroides species are predominantly located in the gut, forming a significant part of the gut microbiota, and play a crucial role in nutrient absorption and metabolism. Their presence is vital for the breakdown of complex carbohydrates and dietary fibers, which humans are unable to digest on their own. By fermenting these substrates, Bacteroides produce short-chain fatty acids (SCFAs) such as butyrate, which serve as a primary energy source for gut epithelial cells and are linked to various health benefits, including anti-inflammatory properties and improved gut barrier function. Research has shown that variations in Bacteroides populations, including Bacteroides sp. 1_1_14, are associated with several health conditions, such as obesity, inflammatory bowel disease, and colorectal cancer. These microbes also have implications in the synthesis of vitamins and other essential nutrients, underpinning their importance in human health. Additionally, their adaptability to different substrates and environments makes them an intriguing subject for studies on gut microbiome dynamics and their potential use in probiotic therapies and gastrointestinal health. |
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