| Description | Bacteroides sp. D20 is a gram-negative, rod-shaped bacterium classified as an obligate anaerobe, thriving optimally in mesophilic temperature ranges (20-45°C) and exhibiting heterotrophic metabolic capabilities. This microbe is primarily found in the human gastrointestinal tract, where it plays a crucial role in the digestion of complex carbohydrates, as well as in other body sites such as the oral cavity and the intestines of various animals. Being gram-negative, Bacteroides sp. D20 possesses a thin peptidoglycan layer surrounded by an outer membrane composed of lipopolysaccharides, which can contribute to its resistance against certain antibiotics. Its rod shape allows for efficient colonization and movement within the gut environment, facilitating interactions with the gut flora and the host's immune system. As an obligate anaerobe, Bacteroides sp. D20 survives and thrives in oxygen-depleted environments, using fermentation to derive energy from organic substrates in the absence of oxygen. As a heterotroph, Bacteroides sp. D20 relies on organic compounds for growth, breaking down dietary fibers and other polysaccharides into short-chain fatty acids that provide energy to both the bacterium and the host. This metabolic function is essential for maintaining gut health, supporting gut barrier function, and regulating immune responses. A notable aspect of Bacteroides sp. D20 is its ability to produce enzymes that degrade complex polysaccharides, playing a significant role in the human diet's fiber breakdown. Furthermore, this microbe has been the focus of research into its potential therapeutic applications, including the modulation of gut microbiota to combat obesity and metabolic diseases. Its unique capabilities underline the essential role of the gut microbiome in human health and disease prevention. |
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