| Description | Cedecea davisae is a gram-negative, rod-shaped bacterium, categorized as a mesophile, a chemoheterotroph, and an obligate aerobe. Found predominantly in clinical settings, it can be isolated from various body sites, including urine, blood, respiratory secretions, and wound sites, particularly in immunocompromised individuals. As a gram-negative organism, Cedecea davisae possesses a thin peptidoglycan layer surrounded by an outer membrane, which facilitates its resistance to certain antibiotics and contributes to its pathogenic potential. Its rod shape allows for motility and adaptation in various environments, which is particularly relevant in the human body where it encounters different niches. The mesophilic nature of this microbe indicates its optimal growth temperature range is around 30-37°C, aligning well with the human body's temperature, thus enhancing its ability to thrive in host tissues. Cedecea davisae's classification as a chemoheterotroph signifies its reliance on organic compounds for both energy and carbon, which it derives from the host's metabolic processes. Being an obligate aerobe, it necessitates oxygen for survival, using it to generate ATP through aerobic respiration, which can play a role in its pathogenicity and survival in oxygen-rich environments like the bloodstream. In terms of clinical significance, Cedecea davisae can be associated with opportunistic infections, particularly in vulnerable populations. Its presence in healthcare settings raises concerns regarding antibiotic resistance, given its gram-negative nature. Studies have shown that Cedecea davisae can adapt to various therapeutic interventions, making understanding its biology essential for managing infections it may cause. Additionally, its environmental persistence suggests that it may serve as a potential indicator of hospital-associated pathogens. |
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