| Description | Lachnospiraceae bacterium TF01-11 is a nonsporulating, fermentative microbe classified within the Lachnospiraceae family, primarily residing in the intestinal microflora of animals. This bacterium exhibits a chemoheterotrophic metabolism, capable of breaking down complex organic compounds to derive energy. Notably, TF01-11 participates in the production of butyrate, a short-chain fatty acid (SCFA) recognized for its pivotal role in colonic health and as an energy source for colonic epithelial cells.TF01-11's metabolic capabilities extend to hydrogen metabolism, lactate production, and the synthesis of acetate, all of which contribute to its versatile role in gut fermentation processes. Additionally, this microbe is adept at degrading various amino acids, including tryptophan, glutamate, lysine, and arginine, further illustrating its importance in the complex ecosystem of the gut microbiota. These biochemical processes not only aid in nutrient absorption but also influence the local pH and microbial composition, thereby impacting overall gastrointestinal health. Ecologically, Lachnospiraceae bacterium TF01-11 highlights the intricate interplay between microbial communities and host health. Its ability to produce butyrate and other fermentation products positions it as a key player in maintaining gut homeostasis, influencing immune responses, and potentially mitigating conditions such as inflammatory bowel disease. Understanding the functional dynamics of such beneficial microbes is critical for developing novel probiotic therapies aimed at restoring or enhancing gut health. |
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